Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.52 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.52 |
| ▸ | ALB | P02768 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.52 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.45 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.44 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.44 |
| ▸ | POLG | P54098 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6917219 | 1.00 | POLB (0.53) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL8641980 | 0.88 | LMNA (0.51) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL16790158 | 0.86 | LMNA (0.51) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL29492643 | 0.84 | LMNA (0.49) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL26189594 | 0.83 | POLB (0.61) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL12149462 | 0.83 | POLB (0.61) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL17533886 | 0.83 | POLB (0.61) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL14639912 | 0.83 | POLB (0.61) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL12836954 | 0.83 | POLB (0.61) | POLBLMNAPDE3ACACNA1FALB | |
| SCHEMBL12352445 | 0.83 | POLB (0.61) | POLBLMNAPDE3ACACNA1FALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4299736-A2 | HYDROLASES AND USES THEREOF | Vilnius University (LT) | 2024-01-03 | — | — | EP | disclosed |
| EP-1084266-B1 | THE APPLICATION OF 5'-MODIFIED NUCLEOTIDES IN MOLECULAR BIOLOGY AND MEDICINE | EUROP LAB MOLEKULARBIOLOG (DE) | 2004-06-30 | — | — | EP | disclosed |
| US-6500663-B1 | TREATING A SUBJECT AFFLICTED WITH A KAPOSI'S SARCOMA CAUSED BY KAPOSI'S SARCOMA ASSOCIATED HERPESVIRUS WHICH COMPRISES ADMINISTERING A NUCLEOSIDE ANALOG OR AN ANTISENSE NUCLEIC ACID | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2002-12-31 | — | — | US | disclosed |
| EP-1084266-A2 | 5'-MODIFIED NUCLEOTIDES AND THE APPLICATION THEREOF IN MOLECULAR BIOLOGY AND MEDICINE | Europäisches Laboratorium für Molekularbiologie (DE) | 2001-03-21 | — | — | EP | disclosed |
| EP-0934333-A4 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | UNIV COLUMBIA (US) | 1999-11-03 | — | — | EP | disclosed |
| EP-0804547-A4 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | UNIV COLUMBIA (US) | 1999-11-03 | — | — | EP | disclosed |
| WO-1999053087-A2 | 5'-MODIFIED NUCLEOTIDES AND THE APPLICATION THEREOF IN MOLECULAR BIOLOGY AND MEDICINE | Europäisches Laboratorium für Molekularbiologie (EMBL) (DE) | 1999-10-21 | — | — | WO | disclosed |
| EP-0934333-A1 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | The Trustees of Columbia University in the City of New York (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0891374-A4 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | UNIV COLUMBIA (US) | 1999-04-07 | — | — | EP | disclosed |
| EP-0891374-A1 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | The Trustees of Columbia University in the City of New York (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1998004576-A1 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1998-02-05 | — | — | WO | disclosed |
| EP-0804547-A1 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | The Trustees of Columbia University in the City of New York (US) | 1997-11-05 | — | — | EP | disclosed |
| WO-1997027208-A1 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1997-07-31 | — | — | WO | disclosed |
| WO-1996015779-A1 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1996-05-30 | — | — | WO | disclosed |
| EP-0427843-A1 | SPECIFIC INHIBITOR FOR RETROVIRUS REVERSE TRANSCRIPTASE, AND ITS APPLICATION AS A MEDICAMENT. | PASTEUR INSTITUT (FR) | 1991-05-22 | — | — | EP | disclosed |
| WO-1990014825-A1 | SPECIFIC INHIBITOR FOR RETROVIRUS REVERSE TRANSCRIPTASE, AND ITS APPLICATION AS A MEDICAMENT | INSTITUT PASTEUR (FR) | 1990-12-13 | — | — | WO | disclosed |