Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 0.70 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.54 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | EEF2K | O00418 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | IAPP | P10997 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6917697 | 1.00 | GABBR2 (0.70) | GABBR2GABBR1PTGS1PTGS2TNFRSF1A | |
| SCHEMBL9657108 | 0.87 | GABBR2 (0.72) | GABBR2GABBR1PTGS1PTGS2TNFRSF1A | |
| SCHEMBL6915895 | 0.86 | GABBR2 (0.76) | GABBR2GABBR1PTGS1PTGS2TNFRSF1A | |
| SCHEMBL225772 | 0.85 | GABBR2 (0.75) | GABBR2GABBR1PTGS1PTGS2TNFRSF1A | |
| SCHEMBL10001228 | 0.85 | GABBR2 (0.75) | GABBR2GABBR1PTGS1PTGS2TNFRSF1A | |
| SCHEMBL225771 | 0.85 | GABBR2 (0.75) | GABBR2GABBR1PTGS1PTGS2TNFRSF1A | |
| SCHEMBL8371054 | 0.84 | GABBR2 (0.68) | GABBR2GABBR1PTGS1PTGS2TNFRSF1A | |
| SCHEMBL4450576 | 0.84 | GABBR2 (0.68) | GABBR2GABBR1PTGS1PTGS2TNFRSF1A | |
| SCHEMBL9227326 | 0.84 | GABBR2 (0.68) | GABBR2GABBR1PTGS1PTGS2TNFRSF1A | |
| SCHEMBL4450572 | 0.84 | GABBR2 (0.68) | GABBR2GABBR1PTGS1PTGS2TNFRSF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026245-A2 | SUBSTITUTED PHOSPHONATE COMPOUNDS HAVING BONE ANABOLIC ACTIVITY | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | disclosed |
| EP-0316790-B1 | RHODANINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS AND THEIR USE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-08-11 | — | — | EP | disclosed |
| US-4897406-A | CHEMICAL MEDIATOR INHIBITORS INCLUDING LEUKOTRIENES; ANTIALLERGENS; BRONCHODILATOR AND ANTIICHEMIC AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| EP-0316790-A1 | Rhodanine derivatives, a process for their preparation, pharmaceutical compositions and their use | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-05-24 | — | — | EP | disclosed |
| EP-0057881-B1 | AN ANTI-INFLAMMATORY, ANALGESIC, AND ANTIPYRETIC PHARMACEUTICAL COMPOSITION, AND METHOD FOR PRODUCING IT | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1985-12-04 | — | — | EP | disclosed |
| US-4440784-A | 3,5-DI-TERT-BUTYL-4-HYDROXYSTYRENE DERIVATIVE | KANEGAFUCHI CHEMICAL INDUSTRY COMPANY, LTD. (JP) | 1984-04-03 | — | — | US | disclosed |
| EP-0057881-A2 | An anti-inflammatory, analgesic, and antipyretic pharmaceutical composition, and method for producing it | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-08-18 | — | — | EP | disclosed |
| US-4281080-A | TACKIFIERS FOR RUBBERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| US-4010140-A | Age resistant resin compositions and admixtures useful as adhesives | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1977-03-01 | — | — | US | disclosed |