SCHEMBL6917783

SCHEMBL6917783

Cc1cc(C)nc(N2C(C)CN(c3ccnc([C@@H](C)O)n3)C[C@H]2C)n1

nearest known ligand 0.82

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SORD Q00796 19/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6294670 1.00 SORD (0.82) SORD
SCHEMBL6297780 0.91 SORD (0.82) SORD
SCHEMBL6297887 0.90 SORD (1.00) SORD
SCHEMBL6294418 0.89 SORD (0.82) SORD
SCHEMBL6297905 0.88 SORD (0.80) SORD
SCHEMBL6818853 0.86 SORD (1.00) SORD
SCHEMBL6293142 0.86 SORD (1.00) SORD
SCHEMBL7249196 0.86 SORD (1.00) SORD
SCHEMBL6294633 0.86 SORD (1.00) SORD
SCHEMBL6298953 0.86 SORD (1.00) SORD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1337271-B1 COMBINATION OF GABA AGONISTS AND SORBITOL DEHYDROGENASE INHIBITORS PFIZER PROD INC (US) 2004-11-03 EP claimed