Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 10/20 | 0.41 |
| ▸ | GRPR | P30550 | 9/20 | 0.41 |
| ▸ | FPR1 | P21462 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6180744 | 0.83 | NMBR (0.48) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6179976 | 0.79 | NMBR (0.65) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6254953 | 0.70 | NMBR (0.49) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6181113 | 0.69 | NMBR (0.53) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL7192683 | 0.69 | NMBR (0.67) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6250491 | 0.69 | NMBR (0.52) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6254317 | 0.68 | NMBR (0.50) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6184335 | 0.67 | NMBR (0.64) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL7193534 | 0.67 | NMBR (0.49) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL6253551 | 0.67 | NMBR (0.49) | NMBRGRPRFPR1AGTR1GPR65 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087561-A1 | Treatment of sexual dysfunction | WARNER-LAMBERT COMPANY LLC | 2004-05-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087561-A1 | Treatment of sexual dysfunction | BRS3, MME, ECE1 | NMBR 258/4885GRPR 199/4885FPR1 632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.