Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 7/20 | 0.65 |
| ▸ | EGLN1 | Q9GZT9 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.41 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16281892 | 0.82 | VEGFA (0.74) | VEGFAEGLN1MEN1BRCA1KMT2A | |
| SCHEMBL5240905 | 0.79 | VEGFA (1.00) | VEGFAEGLN1MEN1BRCA1KMT2A | |
| SCHEMBL12649393 | 0.76 | EGLN1 (0.88) | VEGFAEGLN1CYP19A1CYP1A2POLB | |
| SCHEMBL9368814 | 0.72 | CYP19A1 (0.52) | CYP19A1CYP11B1CYP11B2TBXAS1QPCT | |
| SCHEMBL12598863 | 0.71 | EGLN1 (0.63) | VEGFAEGLN1MEN1KMT2APOLB | |
| SCHEMBL19158006 | 0.70 | EGLN1 (0.55) | VEGFAEGLN1MEN1KMT2APOLB | |
| SCHEMBL14900099 | 0.68 | EGLN1 (0.69) | VEGFAEGLN1MEN1KMT2APOLB | |
| SCHEMBL15314773 | 0.67 | VEGFA (0.75) | VEGFAEGLN1MEN1BRCA1KMT2A | |
| SCHEMBL19157494 | 0.67 | EGLN1 (0.65) | VEGFAEGLN1MEN1KMT2APOLB | |
| SCHEMBL12598814 | 0.67 | EGLN1 (0.68) | VEGFAEGLN1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040097560-A1 | N-alkyl-4-methyleneamino-3-hydroxy-2-pyridones | THE PROCTER & GAMBLE COMPANY | 2004-05-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097560-A1 | N-alkyl-4-methyleneamino-3-hydroxy-2-pyridones | IL17A, CYP51A1, CD4 | VEGFA 3112/4885EGLN1 926/4885MEN1 1328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.