Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10707887 | 0.77 | HTR2C (0.45) | HTR3AHTR2CSIGMAR1DRD2HTR3E | |
| SCHEMBL615912 | 0.76 | HTR2C (0.44) | HTR3AHTR2CSIGMAR1DRD2HTR3E | |
| SCHEMBL5944589 | 0.67 | CA1 (0.46) | HTR3AHTR2CSIGMAR1DRD2HTR3E | |
| SCHEMBL372440 | 0.66 | CA1 (0.44) | HTR3AHTR2CSIGMAR1DRD2HTR3E | |
| SCHEMBL8815732 | 0.62 | CA1 (0.44) | CYP2C19LMNACA12CA1CA2 | |
| 1,2-Dimethoxybenzene SCHEMBL27567930 | 0.59 | CA1 (0.87) | LMNAMAPTCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL9069817 | 0.59 | HTR3A (0.93) | HTR3ASIGMAR1DRD2HTR3EHTR3B | |
| 1,2-Dimethoxybenzene SCHEMBL5308636 | 0.59 | CA1 (1.00) | LMNAMAPTCA12CA1CA2 | |
| 1,2-Dimethoxybenzene SCHEMBL29351917 | 0.59 | CA1 (1.00) | LMNAMAPTCA12CA1CA2 | |
| 1,2-Dimethoxybenzene SCHEMBL105872 | 0.59 | CA1 (1.00) | LMNAMAPTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686321-B2 | MIXTURE; LUBRICANT OIL ADDITIVE | CASTROL LIMITED (GB) | 2004-02-03 | — | — | US | claimed |