Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 19/20 | 0.83 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.62 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1647580 | 0.91 | LRRK2 (1.00) | LRRK2SGMS2 | |
| SCHEMBL6917887 | 0.90 | LRRK2 (0.83) | LRRK2SGMS2SRPK3 | |
| SCHEMBL1647479 | 0.90 | LRRK2 (1.00) | LRRK2SGMS2SRPK3 | |
| SCHEMBL1647862 | 0.88 | LRRK2 (1.00) | LRRK2SGMS2SRPK3 | |
| SCHEMBL10323275 | 0.87 | LRRK2 (1.00) | LRRK2SGMS2SRPK3 | |
| SCHEMBL1647464 | 0.86 | LRRK2 (1.00) | LRRK2SGMS2SRPK3 | |
| SCHEMBL6917595 | 0.85 | LRRK2 (0.79) | LRRK2SGMS2 | |
| SCHEMBL1647444 | 0.84 | LRRK2 (0.80) | LRRK2SGMS2 | |
| SCHEMBL1647755 | 0.84 | LRRK2 (1.00) | LRRK2SGMS2SRPK3 | |
| SCHEMBL17551772 | 0.84 | SGMS2 (0.83) | LRRK2SGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011038572-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2011-04-07 | — | — | WO | disclosed |