Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25839996 | 0.87 | ALDH1A1 (0.74) | POLBRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL11317939 | 0.86 | POLB (0.60) | POLBRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL11317896 | 0.86 | EPHX2 (0.58) | POLBRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL14426547 | 0.86 | MEN1 (0.68) | POLBRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL3649343 | 0.84 | GAA (0.71) | POLBMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29502867 | 0.82 | KMT2A (0.68) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL18702851 | 0.82 | KMT2A (0.68) | RAB9AMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL257816 | 0.81 | EPHX2 (0.76) | POLBRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL11900270 | 0.81 | EPHX2 (0.81) | POLBRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL2010056 | 0.81 | POLB (1.00) | POLBRAB9AMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022528-A2 | ARYLGLYCINE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |