Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | TET3 | O43151 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | ASPH | Q12797 | 1/20 | 0.37 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.37 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.37 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.37 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.37 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.37 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8369280 | 0.87 | ALDH1A1 (0.50) | ALDH1A1MAPK1SRD5A2KDM4EMAPT | |
| SCHEMBL29950379 | 0.85 | TSHR (0.51) | ALDH1A1MAPK1MAPTTSHRNPC1 | |
| Hydrochloric Acid SCHEMBL28791571 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPK1SRD5A2KDM4EMAPT | |
| SCHEMBL3275980 | 0.73 | ALDH1A1 (0.36) | ALDH1A1KDM4EMAPTTDP1CA12 | |
| SCHEMBL4433792 | 0.73 | TSHR (0.53) | ALDH1A1MAPK1TSHRNPC1RAB9A | |
| SCHEMBL18918201 | 0.72 | BLM (0.40) | MAPTTDP1TSHRTP53 | |
| SCHEMBL657497 | 0.72 | MAPT (0.39) | ALDH1A1MAPK1KDM4EMAPTTDP1 | |
| SCHEMBL5765607 | 0.71 | ALDH1A1 (0.51) | ALDH1A1MAPK1SRD5A2KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL29118231 | 0.71 | TSHR (0.50) | ALDH1A1MAPK1TSHRNPC1RAB9A | |
| SCHEMBL3199131 | 0.70 | ALDH1A1 (0.47) | ALDH1A1MAPK1SRD5A2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3873896-A1 | TRICYCLIC COMPOUNDS AS STING AGONISTS, AND PREPARATION METHODS AND MEDICINAL USES THEREOF | Jiangsu Hengrui Medicine Co., Ltd. (CN) | 2021-09-08 | — | — | EP | disclosed |
| WO-2020124059-A1 | TRICYCLIC COMPOUNDS AS STING AGONISTS, AND PREPARATION METHODS AND MEDICINAL USES THEREOF | Eternity Bioscience Inc. (US) | 2020-06-18 | — | — | WO | disclosed |
| WO-2004014389-A1 | 3,4-DIHYDROQUINOLIN-2-ONE, 5,6-FUSED OXAZIN-3-ONE, AND 5,6-FUSED THIAZIN-3-ONE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |
| EP-0197807-A1 | Pyrazolobenzoxazine derivatives, their salts, process and preparation intermediates, use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1986-10-15 | — | — | EP | disclosed |