Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | APOBEC3B | Q9UH17 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28192657 | 0.82 | L3MBTL1 (0.55) | L3MBTL1EPHX2KMT2AMEN1RAB9A | |
| SCHEMBL447082 | 0.82 | L3MBTL1 (0.51) | L3MBTL1EPHX2KMT2AMEN1RAB9A | |
| SCHEMBL12376722 | 0.77 | SMN1; SMN2 (0.59) | L3MBTL1EPHX2KMT2AMEN1RAB9A | |
| SCHEMBL12561259 | 0.77 | L3MBTL1 (0.59) | L3MBTL1EPHX2KMT2AMEN1RAB9A | |
| SCHEMBL13701751 | 0.77 | KMT2A (0.48) | L3MBTL1EPHX2KMT2AMEN1RAB9A | |
| Hydrochloric Acid SCHEMBL30612668 | 0.77 | L3MBTL1 (0.46) | L3MBTL1EPHX2KMT2AMEN1RAB9A | |
| SCHEMBL3370719 | 0.76 | POLB (0.59) | L3MBTL1EPHX2KMT2AMEN1RAB9A | |
| SCHEMBL657937 | 0.74 | POLB (0.47) | L3MBTL1EPHX2KMT2AMEN1RAB9A | |
| SCHEMBL2366245 | 0.74 | POLB (0.44) | L3MBTL1EPHX2KMT2AMEN1RAB9A | |
| SCHEMBL4004484 | 0.74 | KMT2A (0.45) | L3MBTL1EPHX2KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022536-A1 | NEW HETEROCYCLIC AMIDE COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (US) | 2004-03-18 | — | — | WO | disclosed |