Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 4/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920452 | 0.92 | SCN9A (0.36) | SCN9AF2MC4RGPBAR1F10 | |
| SCHEMBL6919923 | 0.86 | F2 (0.39) | F2GPBAR1MEN1KMT2AF10 | |
| SCHEMBL6919276 | 0.84 | F2 (0.38) | SCN9AF2MC4RF10PLAT | |
| SCHEMBL6077330 | 0.83 | F2 (0.39) | SCN9AF2MC4RF10PLAT | |
| SCHEMBL6921239 | 0.81 | F2 (0.38) | F2GPBAR1MEN1KMT2AF10 | |
| SCHEMBL6919762 | 0.79 | F2 (0.38) | F2GPBAR1MEN1KMT2AF10 | |
| SCHEMBL6919684 | 0.79 | F2 (0.42) | F2GPBAR1MEN1KMT2AF10 | |
| SCHEMBL6922164 | 0.78 | F2 (0.43) | F2GPBAR1MEN1KMT2AF10 | |
| SCHEMBL6919834 | 0.77 | ALDH1A1 (0.49) | F2GPBAR1MEN1KMT2AF10 | |
| SCHEMBL6919210 | 0.77 | F2 (0.39) | F2GPBAR1MEN1KMT2AF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004032834-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2004-04-22 | — | — | WO | disclosed |