⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL123776 | 0.69 | TDP1 (0.33) | — | |
| SCHEMBL12484858 | 0.64 | CRBN (0.31) | — | |
| SCHEMBL10774340 | 0.60 | CRBN (0.30) | — | |
| SCHEMBL28198734 | 0.60 | CRBN (0.33) | — | |
| SCHEMBL11680905 | 0.58 | — | — | |
| SCHEMBL31310637 | 0.57 | — | — | |
| SCHEMBL8339258 | 0.55 | BACE1 (0.32) | — | |
| SCHEMBL2303039 | 0.54 | — | — | |
| SCHEMBL5143191 | 0.53 | — | — | |
| SCHEMBL19348418 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4358970-A1 | COMPOUNDS FOR TREATING GENETIC DISEASES | Zikani Therapeutics, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022251730-A1 | COMPOUNDS FOR TREATING GENETIC DISEASES | ZIKANI THERAPEUTICS, INC. (US) | 2022-12-01 | — | — | WO | disclosed |
| WO-2004014909-A1 | FUSED TETRAHYDROPYRIDINE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |