Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 12/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7160095 | 0.90 | HTR1A (0.63) | HTR1A | |
| SCHEMBL6919604 | 0.89 | HTR1A (0.67) | HTR1A | |
| SCHEMBL7157615 | 0.87 | HTR1A (0.58) | HTR1A | |
| SCHEMBL6819884 | 0.83 | HTR1A (0.69) | HTR1A | |
| SCHEMBL6819734 | 0.83 | HTR1A (0.69) | HTR1A | |
| SCHEMBL16433155 | 0.82 | HTR1A (1.00) | HTR1A | |
| SCHEMBL22369365 | 0.81 | HTR1A (0.79) | HTR1A | |
| SCHEMBL16433314 | 0.80 | HTR1A (1.00) | HTR1A | |
| SCHEMBL6920034 | 0.79 | HTR1A (0.66) | HTR1A | |
| SCHEMBL6819326 | 0.78 | HTR1A (0.65) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004041815-A1 | INDOLE DERIVATIVE WITH 5HT1A AFFINITY | MERCK PATENT GMBH (DE) | 2004-05-21 | — | — | WO | disclosed |