Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4277035 | 0.73 | TSHR (0.33) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL2067640 | 0.68 | TRPA1 (0.44) | TRPA1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL5862157 | 0.66 | — | — | |
| SCHEMBL4559633 | 0.65 | TRPA1 (0.36) | TRPA1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL4239372 | 0.64 | TRPA1 (0.47) | TRPA1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL1457346 | 0.64 | — | — | |
| SCHEMBL3804612 | 0.64 | — | — | |
| SCHEMBL5862159 | 0.64 | — | — | |
| SCHEMBL950500 | 0.64 | — | — | |
| SCHEMBL392205 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004020402-A1 | SULPHONYLAMINO DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-03-11 | — | — | WO | claimed |
| WO-2004020402-A1 | SULPHONYLAMINO DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | DE NOVO PHARMACEUTICALS LIMITED (GB) | 2004-03-11 | — | — | WO | disclosed |