Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6538327 | 0.91 | MAPT (0.38) | TP53POLBCGASNTRK1FGFR1 | |
| SCHEMBL6539045 | 0.84 | ALDH1A1 (0.44) | TP53POLBADORA2AKDM4EMAPT | |
| SCHEMBL6539012 | 0.83 | POLB (0.42) | TP53POLBADORA2AKDM4EMAPT | |
| SCHEMBL6920831 | 0.82 | TP53 (0.39) | TP53POLBADORA2AKDM4EMAPT | |
| SCHEMBL6539298 | 0.81 | BAZ2B (0.49) | TP53POLBNTRK1FGFR1FGFR2 | |
| SCHEMBL6538393 | 0.80 | TP53 (0.36) | TP53POLBADORA2AKDM4EMAPT | |
| SCHEMBL6538457 | 0.79 | MAPT (0.41) | TP53POLBFGFR1FGFR2FGFR4 | |
| SCHEMBL6538844 | 0.79 | TP53 (0.37) | TP53POLBADORA2AMAPTLMNA | |
| SCHEMBL6538773 | 0.78 | KMT2A (0.37) | TP53POLBKDM4EMAPT | |
| SCHEMBL6538474 | 0.78 | RET (0.41) | TP53POLBADORA2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022540-A2 | PYRIDAZINONE AND PYRIDONE DERIVATIVES AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-18 | — | — | WO | disclosed |