Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.62 |
| ▸ | BCR | P11274 | 6/20 | 0.62 |
| ▸ | CTSS | P25774 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | PRKDC | P78527 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28195198 | 0.91 | PRKDC (0.55) | ABL1BCRCTSSCTSKMAPT | |
| SCHEMBL5863233 | 0.87 | HDAC8 (0.62) | ABL1MAPTALDH1A1GAAEPHX2 | |
| SCHEMBL5863308 | 0.85 | EPHX2 (0.72) | MAPTALDH1A1GLAGAAEPHX2 | |
| SCHEMBL28842178 | 0.83 | PRKDC (0.51) | ABL1BCRCTSSCTSKMAPT | |
| SCHEMBL19831261 | 0.82 | PRKDC (0.48) | ABL1BCRCTSSCTSKMAPT | |
| SCHEMBL7980595 | 0.82 | MAPT (0.62) | MAPTALDH1A1GAAMAPK1RAB9A | |
| SCHEMBL3997021 | 0.80 | ABL1 (0.60) | ABL1BCRCTSSCTSKMAPT | |
| SCHEMBL4004651 | 0.79 | ABL1 (0.61) | ABL1BCRCTSSCTSKMAPT | |
| SCHEMBL17281260 | 0.78 | PRKDC (0.51) | ABL1BCRCTSSCTSKMAPT | |
| SCHEMBL4884549 | 0.78 | MAPT (0.68) | ABL1BCRMAPTMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058713-A1 | DIFFERENTIAL TUMOR CYTOTOXOCITY COMPOUNDS AND COMPOSITIONS | IRM LLC (BM) | 2004-07-15 | — | — | WO | disclosed |