Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | KDM1A | O60341 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | SYK | P43405 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30855000 | 0.92 | KDM1A (0.65) | MAPTMAPK1TP53KDM1ALMNA | |
| SCHEMBL8977928 | 0.90 | VCP (0.63) | MAPTMAPK1TP53KDM1AMEN1 | |
| SCHEMBL30854958 | 0.89 | MAPT (0.65) | MAPTMAPK1TP53KDM1AHTT | |
| SCHEMBL7066138 | 0.86 | LMNA (0.56) | MAPTMAPK1TP53LMNAMEN1 | |
| SCHEMBL9093746 | 0.85 | LMNA (0.71) | MAPTMAPK1TP53LMNAMEN1 | |
| SCHEMBL12285459 | 0.84 | MAPT (0.52) | MAPTMAPK1TP53KDM1ALMNA | |
| SCHEMBL31025628 | 0.84 | MAPT (0.49) | MAPTMAPK1TP53KDM1ANPC1 | |
| SCHEMBL25188289 | 0.83 | RAB9A (0.58) | MAPTMAPK1TP53HTTNPC1 | |
| SCHEMBL3080226 | 0.83 | HDAC8 (0.57) | MAPTMAPK1TP53LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL5339521 | 0.83 | LMNA (0.52) | MAPTMAPK1TP53LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218576-B1 | CONDENSING ARYLAMINE IN PRESENCE OF ANHYDROUS ALUMINUM CHLORIDE AND CALCIUM CHLORIDE; ARYLATION | SANKIO CHEMICAL CO., LTD. (JP) | 2001-04-17 | — | — | US | disclosed |
| EP-0273418-B1 | Heat-sensitive recording material using chromeno compound | KANZAKI PAPER MFG CO LTD (JP) | 1993-11-24 | — | — | EP | disclosed |
| US-4803193-A | COLORFASTNESS; READABLE BY OPTICAL CHARACTER-READING DEVICES | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1989-02-07 | — | — | US | disclosed |
| EP-0273418-A2 | Heat-sensitive recording material using chromeno compound | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1988-07-06 | — | — | EP | disclosed |