Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.78 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 2/20 | 0.49 |
| ▸ | BRD2 | P25440 | 1/20 | 0.49 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.49 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3354461 | 0.89 | SMN1; SMN2 (0.78) | SMN1; SMN2KDM4EALDH1A1ATMHTT | |
| Hydrochloric Acid SCHEMBL6920695 | 0.88 | SMN1; SMN2 (0.76) | SMN1; SMN2KDM4EALDH1A1ATMHTT | |
| SCHEMBL13306606 | 0.82 | KDM4E (0.68) | SMN1; SMN2KDM4EALDH1A1ATMHTT | |
| SCHEMBL11454823 | 0.82 | BRD4 (0.68) | SMN1; SMN2KDM4EALDH1A1HTTRAB9A | |
| SCHEMBL3348497 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2KDM4EALDH1A1ATMHTT | |
| Hydrochloric Acid SCHEMBL9356599 | 0.77 | KDM4E (0.61) | SMN1; SMN2KDM4EALDH1A1ATMHTT | |
| SCHEMBL11535104 | 0.76 | BRD4 (0.49) | SMN1; SMN2KDM4EALDH1A1ATMHTT | |
| SCHEMBL13306613 | 0.75 | KDM4E (0.67) | SMN1; SMN2KDM4EALDH1A1ATMHTT | |
| SCHEMBL6919159 | 0.75 | EGLN1 (0.68) | SMN1; SMN2KDM4EATMRAB9APOLB | |
| SCHEMBL4997689 | 0.75 | ATM (0.76) | SMN1; SMN2KDM4EALDH1A1ATMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046122-A2 | BENZOXAZOLE, BENZTHIAZOLE AND BENZIMIDAZOLE ACID DERIVATIVES AND THEIR USE AS HEPARANASE INHIBITORS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2004-06-03 | — | — | WO | disclosed |