Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CAD | P27708 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920806 | 1.00 | ECE1 (0.39) | ECE1ALOX15CAD | |
| SCHEMBL6920799 | 0.86 | GABRR1 (0.34) | ALOX15CAD | |
| SCHEMBL7347883 | 0.73 | ECE1 (0.44) | ECE1ALOX15CAD | |
| SCHEMBL7352891 | 0.73 | ECE1 (0.44) | ECE1ALOX15CAD | |
| SCHEMBL7034111 | 0.72 | ECE1 (0.42) | ECE1 | |
| SCHEMBL3856802 | 0.72 | ECE1 (0.42) | ECE1 | |
| SCHEMBL16128209 | 0.72 | SUCNR1 (0.33) | ALOX15 | |
| SCHEMBL27597011 | 0.72 | KMT2A (0.42) | ALOX15 | |
| SCHEMBL18306946 | 0.72 | ECE1 (0.31) | ECE1 | |
| SCHEMBL27597009 | 0.72 | KMT2A (0.42) | ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480999-A2 | (SUBSTITUTED)ACYL DIPEPTIDYL INHIBITORS OF THE ICE/CED-3 FAMILY OF CYSTEINE PROTEASES | Idun Pharmaceuticals (US) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003072528-A2 | (SUBSTITUTED)ACYL DIPEPTIDYL INHIBITORS OF THE ICE/CED-3 FAMILY OF CYSTEINE PROTEASES | IDUN PHARMACEUTICALS, INC. (US) | 2003-09-04 | — | — | WO | disclosed |