Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.32 |
| ▸ | CAD | P27708 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | GNPAT | O15228 | 1/20 | 0.30 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16128209 | 0.86 | SUCNR1 (0.33) | GABRR1LMNAALOX15GNPATSLC22A6 | |
| SCHEMBL6920806 | 0.86 | ECE1 (0.39) | ALOX15CAD | |
| SCHEMBL6920795 | 0.86 | ECE1 (0.39) | ALOX15CAD | |
| SCHEMBL31360784 | 0.84 | CA2 (0.39) | GNPATCA2CA4 | |
| SCHEMBL8450154 | 0.74 | ITGB3 (0.34) | GABRR1LMNAENPEPGNPATSLC22A6 | |
| SCHEMBL17773049 | 0.74 | ITGB3 (0.34) | GABRR1LMNAENPEPGNPATSLC22A6 | |
| SCHEMBL27404077 | 0.73 | GABRR1 (0.43) | GABRR1LMNASLC22A6 | |
| SCHEMBL8729434 | 0.73 | SLC22A6 (0.36) | GABRR1LMNAENPEPGNPATSLC22A6 | |
| SCHEMBL14490960 | 0.73 | SLC22A6 (0.36) | GABRR1LMNAENPEPGNPATSLC22A6 | |
| SCHEMBL16348723 | 0.73 | SLC22A6 (0.36) | GABRR1LMNAENPEPGNPATSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480999-A2 | (SUBSTITUTED)ACYL DIPEPTIDYL INHIBITORS OF THE ICE/CED-3 FAMILY OF CYSTEINE PROTEASES | Idun Pharmaceuticals (US) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003072528-A2 | (SUBSTITUTED)ACYL DIPEPTIDYL INHIBITORS OF THE ICE/CED-3 FAMILY OF CYSTEINE PROTEASES | IDUN PHARMACEUTICALS, INC. (US) | 2003-09-04 | — | — | WO | disclosed |