Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 10/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.45 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19884914 | 0.89 | CHRM3 (0.46) | CHRM3BCHEACHECHRNB2CHRNB4 | |
| SCHEMBL10005292 | 0.85 | CHRM3 (0.58) | CHRM3 | |
| Bromide SCHEMBL14937409 | 0.83 | CHRM3 (0.59) | CHRM3CHRM2CHRM1 | |
| SCHEMBL2344944 | 0.79 | BCHE (0.65) | CHRM3BCHEACHECHRNB2CHRNB4 | |
| Bromide SCHEMBL6889492 | 0.78 | BCHE (0.68) | CHRM3BCHEACHECHRNB2CHRNB4 | |
| Water SCHEMBL31012149 | 0.78 | BCHE (0.62) | CHRM3BCHEACHECHRNB2CHRNB4 | |
| Hydrochloric Acid SCHEMBL27524696 | 0.78 | BCHE (0.62) | CHRM3BCHEACHECHRNB2CHRNB4 | |
| SCHEMBL6830020 | 0.77 | CHKA (0.47) | HRH3 | |
| Bromide SCHEMBL14165975 | 0.75 | CHRM3 (0.56) | CHRM3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| Bromide SCHEMBL158788 | 0.71 | CHRNB2 (0.71) | CHRM3CHRNB2CHRNB4CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421518-A2 | AGGLOMERATE FORMULATIONS INCLUDING ACTIVE PHARMACEUTICAL AGENTS WITH TARGETED PARTICLE SIZES | Schering Corporation (US) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010124203-A2 | AGGLOMERATE FORMULATIONS INCLUDING ACTIVE PHARMACEUTICAL AGENTS WITH TARGETED PARTICLE SIZES | SCHERING CORPORATION (US) | 2010-10-28 | — | — | WO | disclosed |
| EP-2119716-A1 | AZA-BRIDGED-RING COMPOUND | Astellas Pharma Inc. (JP) | 2009-11-18 | — | — | EP | disclosed |
| EP-1442027-A1 | SUBSTITUTED DIPHENYLOXAZOLES, THE SYNTHESIS THEREOF, AND THE USE THEREOF AS FLUORESCENCE PROBES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003031419-A1 | SUBSTITUTED DIPHENYLOXAZOLES, THE SYNTHESIS THEREOF, AND THE USE THEREOF AS FLUORESCENCE PROBES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2003-04-17 | — | — | WO | disclosed |