Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MERTK | Q12866 | 6/20 | 0.44 |
| ▸ | FLT3 | P36888 | 5/20 | 0.44 |
| ▸ | TYRO3 | Q06418 | 5/20 | 0.44 |
| ▸ | GAS6 | Q14393 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9913708 | 0.91 | MERTK (0.50) | PDE4AMERTKFLT3TYRO3GAS6 | |
| SCHEMBL10345298 | 0.86 | KMT2A (0.49) | PDE4AKMT2AMERTKFLT3TYRO3 | |
| SCHEMBL11198498 | 0.84 | PDE4A (0.66) | PDE4AKMT2ARAB9ALMNA | |
| SCHEMBL14725039 | 0.84 | TLR7 (0.46) | PDE4AKMT2ARAB9AMERTKFLT3 | |
| SCHEMBL6679846 | 0.83 | PDE4A (0.69) | PDE4AKMT2ARAB9ALMNACTSS | |
| SCHEMBL2783761 | 0.82 | KMT2A (0.71) | KMT2ALMNA | |
| SCHEMBL6677011 | 0.81 | LMNA (0.63) | PDE4AKMT2ARAB9ALMNA | |
| SCHEMBL20694824 | 0.81 | KMT2A (0.81) | KMT2ALMNA | |
| SCHEMBL14522578 | 0.80 | NPSR1 (0.44) | PDE4AKMT2AMERTKFLT3TYRO3 | |
| SCHEMBL20814607 | 0.79 | PDE4A (0.55) | PDE4AKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002036578-A9 | TRIAZINE DERIVATIVES AS LPAAT-B INHIBITORS AND USES THEREOF | BONHAM LYNN (US) | 2004-04-22 | — | — | WO | claimed |
| WO-2002036578-A2 | TRIAZINE DERIVATIVES AS LPAAT-B INHIBITORS AND USES THEREOF | BONHAM LYNN (US) | 2002-05-10 | — | — | WO | claimed |
| WO-2002036578-A9 | TRIAZINE DERIVATIVES AS LPAAT-B INHIBITORS AND USES THEREOF | BONHAM LYNN (US) | 2004-04-22 | — | — | WO | disclosed |
| WO-2002036578-A2 | TRIAZINE DERIVATIVES AS LPAAT-B INHIBITORS AND USES THEREOF | BONHAM LYNN (US) | 2002-05-10 | — | — | WO | disclosed |