Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EIF4EBP1 | Q13541 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6923139 | 0.89 | ALDH1A1 (0.38) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL6497415 | 0.83 | PPARG (0.52) | ALDH1A1MAPTPPARGALOX5APSMN1; SMN2 | |
| SCHEMBL6489299 | 0.83 | PPARG (0.45) | PPARGALOX5APEIF4EBP1VDRNR1H4 | |
| SCHEMBL6491734 | 0.83 | PPARG (0.53) | PPARGALOX5APEIF4EBP1LMNANPSR1 | |
| SCHEMBL6503556 | 0.81 | PPARG (0.42) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL6493004 | 0.81 | PDE2A (0.47) | PPARGALOX5APCYP1A2 | |
| SCHEMBL6487796 | 0.80 | PPARG (0.52) | PPARGSMN1; SMN2LMNA | |
| SCHEMBL6926026 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EHSD17B10HPGD | |
| SCHEMBL6307363 | 0.78 | PPARG (0.51) | ALDH1A1MAPTHSD17B10PPARGALOX5AP | |
| SCHEMBL6488294 | 0.77 | PPARG (0.42) | ALDH1A1MAPTHPGDPPARGSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |