Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 19/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.59 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1893989 | 0.84 | ADORA1 (0.83) | ADORA1ADORA3ADORA2BADORA2A | |
| SCHEMBL1867189 | 0.75 | ADORA1 (1.00) | ADORA1ADORA3ADORA2BADORA2A | |
| SCHEMBL12079618 | 0.75 | ADORA1 (0.52) | ADORA1ADORA3ADORA2BADORA2A | |
| SCHEMBL1867327 | 0.75 | ADORA1 (0.98) | ADORA1ADORA3ADORA2BADORA2A | |
| SCHEMBL1874301 | 0.74 | ADORA1 (0.80) | ADORA1ADORA3ADORA2BADORA2A | |
| SCHEMBL1866329 | 0.71 | ADORA1 (0.77) | ADORA1ADORA3ADORA2BADORA2A | |
| SCHEMBL6920308 | 0.69 | ADORA2B (0.75) | ADORA1ADORA3ADORA2BADORA2A | |
| SCHEMBL12079680 | 0.69 | ADORA1 (1.00) | ADORA1ADORA3ADORA2BADORA2A | |
| SCHEMBL18059627 | 0.68 | ADORA1 (0.81) | ADORA1ADORA3ADORA2BADORA2A | |
| SCHEMBL1866491 | 0.67 | ADORA1 (0.53) | ADORA1ADORA3ADORA2BADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011055391-A1 | SUBSTITUTED FUSED PYRIMIDINE COMPOUNDS, ITS PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-05-12 | — | — | WO | disclosed |