Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | F12 | P00748 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707767 | 0.89 | HIF1A (0.42) | HIF1ANPC1RAB9ALMNACYP1A2 | |
| SCHEMBL6710284 | 0.80 | NPC1 (0.46) | NPC1RAB9ALMNADRD3ALDH1A1 | |
| SCHEMBL6714271 | 0.79 | HIF1A (0.48) | HIF1A | |
| SCHEMBL6711761 | 0.78 | HIF1A (0.34) | HIF1AMAPT | |
| SCHEMBL6710262 | 0.78 | HIF1A (0.42) | HIF1ANPC1RAB9ALMNACYP1A2 | |
| SCHEMBL6713809 | 0.77 | HIF1A (0.43) | HIF1A | |
| SCHEMBL6710550 | 0.77 | HIF1A (0.44) | HIF1ANPC1RAB9ALMNACYP1A2 | |
| SCHEMBL6708868 | 0.77 | HIF1A (0.44) | HIF1ANPC1RAB9ALMNACYP1A2 | |
| SCHEMBL6709076 | 0.77 | LMNA (0.35) | HIF1ALMNACYP1A2MAPTMEN1 | |
| SCHEMBL6713406 | 0.77 | NPC1 (0.41) | NPC1RAB9ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |