Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CCKBR | P32239 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6825377 | 0.94 | NPC1 (0.42) | NPC1RAB9ATHRBALDH1A1MAPT | |
| SCHEMBL6825521 | 0.92 | NPC1 (0.46) | NPC1RAB9ATHRBALDH1A1MAPT | |
| SCHEMBL6827885 | 0.89 | NPC1 (0.45) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL6827769 | 0.88 | EPHX2 (0.49) | NPC1RAB9ATHRBALDH1A1MAPT | |
| SCHEMBL6825035 | 0.88 | NPC1 (0.43) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL6825501 | 0.87 | EPHX2 (0.48) | NPC1RAB9ATHRBALDH1A1MAPT | |
| SCHEMBL6825276 | 0.87 | MEN1 (0.43) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL6822405 | 0.85 | KMT2A (0.50) | ALDH1A1MAPTMEN1KMT2APPARA | |
| SCHEMBL6827533 | 0.84 | RAB9A (0.46) | NPC1RAB9AALDH1A1MAPTLMNA | |
| SCHEMBL6825108 | 0.84 | NPC1 (0.47) | NPC1RAB9AALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087643-A1 | DEFORMYLASE INHIBITOR, PROCESS FOR PREPARING THE SAME, AND ANTIBACTERIAL COMPOSITION COMPRISING THE SAME | PROMEDITECH INC. (KR) | 2004-10-14 | — | — | WO | disclosed |