Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 3/20 | 0.37 |
| ▸ | RXRA | P19793 | 3/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6922621 | 0.91 | NOTUM (0.53) | NOTUMCA1CA2CA9CA4 | |
| SCHEMBL6925346 | 0.89 | NOTUM (0.38) | NOTUMCA1CA2CA9CA4 | |
| SCHEMBL6923532 | 0.88 | NOTUM (0.40) | NOTUMCA1CA2CA9CA4 | |
| SCHEMBL6919734 | 0.80 | NOTUM (0.46) | NOTUMCA1CA2CA9CA12 | |
| SCHEMBL6924641 | 0.77 | KDM1A (0.35) | NOTUMCA1CA2CA9CA4 | |
| SCHEMBL6925271 | 0.76 | TYR (0.38) | RXRAGRIN1GRIN2B | |
| SCHEMBL6922304 | 0.75 | MIF (0.37) | NOTUMMIFKDM1ACAPN1APP | |
| SCHEMBL6922295 | 0.74 | NOTUM (0.37) | NOTUMMIFKDM1ARXRAGRIN1 | |
| SCHEMBL6534143 | 0.74 | GRM1 (0.42) | NOTUMCA1CA2CA9CA4 | |
| SCHEMBL6923496 | 0.71 | NOTUM (0.42) | NOTUMMIFKDM1ARXRAGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106329-A2 | NOVEL ANTIINFECTIVE COMPOUNDS AND THEIR PHARMACEUTICAL COMPOSITIONS | DR. REDDY'S LABORATORIES LTD. (IN) | 2004-12-09 | — | — | WO | disclosed |