Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528580 | 0.83 | HTR6 (0.40) | TYRKCNH2RXRAGRIN1GRIN2B | |
| SCHEMBL6919734 | 0.82 | NOTUM (0.46) | KCNH2RXRAGRIN1GRIN2BMAOA | |
| SCHEMBL6528269 | 0.79 | GRM1 (0.41) | TYRKCNH2PTGS2ALOX15 | |
| SCHEMBL5623713 | 0.78 | ALDH1A1 (0.45) | TYRMAPTRXRAGRIN1GRIN2B | |
| SCHEMBL6922621 | 0.77 | NOTUM (0.53) | RXRAGRIN1GRIN2BMAOA | |
| SCHEMBL6922255 | 0.76 | NOTUM (0.45) | RXRAGRIN1GRIN2B | |
| SCHEMBL6925346 | 0.74 | NOTUM (0.38) | RXRAGRIN1GRIN2BMAOA | |
| SCHEMBL6920471 | 0.72 | TYR (0.39) | TYRMAPTRECQLPTGS2ACHE | |
| SCHEMBL6527434 | 0.72 | TYR (0.39) | TYRMAPTRECQLPTGS2ACHE | |
| SCHEMBL19211452 | 0.69 | KCNH2 (0.59) | KCNH2RXRAGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106329-A2 | NOVEL ANTIINFECTIVE COMPOUNDS AND THEIR PHARMACEUTICAL COMPOSITIONS | DR. REDDY'S LABORATORIES LTD. (IN) | 2004-12-09 | — | — | WO | disclosed |