Quinolinic Acid

Quinolinic Acid

SCHEMBL69230

O=C(O)c1cccnc1C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 1.00
ALDH1A1 P00352 5/20 1.00
ALOX15 P16050 3/20 1.00
MAPT P10636 2/20 1.00
CYP3A4 P08684 1/20 1.00
TSHR P16473 1/20 1.00
BLM P54132 1/20 1.00
AGER Q15109 1/20 1.00
NPSR1 Q6W5P4 1/20 1.00
L3MBTL1 Q9Y468 1/20 1.00
TDP1 Q9NUW8 1/20 0.65
NAPRT Q6XQN6 2/20 0.61
LMNA P02545 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
CYP1A2 P05177 1/20 0.55
GAA P10253 2/20 0.54
ASPH Q12797 2/20 0.53
KDM8 Q8N371 2/20 0.53
DHODH Q02127 1/20 0.52
KMT2A Q03164 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinolinic Acid SCHEMBL29356188 1.00 KDM4E (1.00) KDM4EALDH1A1ALOX15MAPTCYP3A4
Quinolinic Acid SCHEMBL27676801 1.00 KDM4E (1.00) KDM4EALDH1A1ALOX15MAPTCYP3A4
Quinolinic Acid SCHEMBL343618 1.00 KDM4E (1.00) KDM4EALDH1A1ALOX15MAPTCYP3A4
Quinolinic Acid SCHEMBL5361020 0.98 KDM4E (0.96) KDM4EALDH1A1ALOX15MAPTCYP3A4
Quinolinic Acid SCHEMBL1897909 0.98 KDM4E (0.96) KDM4EALDH1A1ALOX15MAPTCYP3A4
Quinolinic Acid SCHEMBL5381551 0.98 KDM4E (0.96) KDM4EALDH1A1ALOX15MAPTCYP3A4
Quinolinic Acid SCHEMBL5674125 0.98 KDM4E (0.96) KDM4EALDH1A1ALOX15MAPTCYP3A4
Quinolinic Acid SCHEMBL21326209 0.98 KDM4E (0.96) KDM4EALDH1A1ALOX15MAPTCYP3A4
Quinolinic Acid SCHEMBL890367 0.98 KDM4E (0.96) KDM4EALDH1A1ALOX15MAPTCYP3A4
Quinolinic Acid SCHEMBL3744925 0.98 KDM4E (0.96) KDM4EALDH1A1ALOX15MAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 15160 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
CN-117210683-B Method for mineralizing and recycling dysprosium ions by bacillus pasteurizer JIANGXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2026-05-26 CN claimed
CN-122081219-A Cryopreservation resuscitation fluid for immune cells and resuscitation method 2026-05-26 CN claimed
US-20260138879-A1 MODIFIED LAYERED DOUBLE HYDROXIDE (LDH), PARTICLES COMPRISING SAID LDH, AND METHOD FOR PRODUCING SAID LDH KISUMA CHEMICALS B V (NL) 2026-05-21 US claimed
EP-3808347-B1 SUBSTANCES FOR TREATMENT OF FATTY LIVER-RELATED CONDITIONS SCANDIBIO THERAPEUTICS AB (SE) 2026-05-20 EP claimed
US-12633376-B2 System and method for risk assessment of autism spectrum disorder TATA CONSULTANCY SERVICES LIMITED (IN) 2026-05-19 US claimed
CN-122036658-A Process for the synthesis of aromatic dicarboxylic acids 环球油品有限责任公司 2026-05-15 CN claimed
WO-2026100590-A1 SYSTEM FOR EVALUATING PERSON SUFFERING FROM COVID-19, METHOD FOR EVALUATING PERSON SUFFERING FROM COVID-19, AND COMPUTER PROGRAM 地方独立行政法人 神奈川県立病院機構 2026-05-15 WO claimed
CN-122031539-A Pine bark polyphenol extract and preparation method and application thereof 北京农学院 2026-05-15 CN claimed
CN-122037917-A Eu (Eu)3+Complex AIE sensor and preparation and fluorescence cycle recognition Cu thereof2+And the use of ATP 陇东学院 2026-05-15 CN claimed
EP-0064378-A2 Affinity chromatography using metal ions The Public Health Laboratory Service Board (GB) 1982-11-10 EP claimed
US-4322355-A Production of 1,3-difunctional compounds NATIONAL DISTILLERS & CHEMICAL CORP. (US) 1982-03-30 US claimed
EP-0023371-A1 Underwater coating composition ASTRAL Société de Peintures et Vernis (FR) 1981-02-04 EP claimed
EP-0001247-A1 Pharmaceutical preparation containing nifedipine and a method for producing the same. KANEBO, LTD. (JP) 1979-04-04 EP claimed
US-4130586-A Process for producing imine compounds MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1978-12-19 US claimed
US-4129517-A PERGLUTARIC ACID STERLING DRUG INC. (US) 1978-12-12 US claimed
US-4120762-A POROUS SUPPORT IMPREGNATED WITH AN ELECTROLYTE, A MARKING COMPOUND AND A NITROGEN-CONTAINING SIX-MEMBERED HETEROCYCLIC AROMATIC CARBOXY ACID ALDEN RESEARCH FOUNDATION (US) 1978-10-17 US claimed
US-4079045-A Esterification of terephthalic acid with an alkylene glycol in the presence of a pyridine dicarboxylic acid compound ALLIED CHEMICAL CORPORATION (US) 1978-03-14 US claimed
US-4076856-A Methyl xanthine antagonism GENERAL FOODS CORPORATION (US) 1978-02-28 US claimed
US-4058613-A Quinoline derivatives having fungicidal activity MONTEDISON S.P.A. (IT) 1977-11-15 US claimed