Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | IDE | P14735 | 1/20 | 0.65 |
| ▸ | MPI | P34949 | 1/20 | 0.65 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.65 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.65 |
| ▸ | DAO | P14920 | 1/20 | 0.64 |
| ▸ | DDO | Q99489 | 1/20 | 0.64 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.51 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31182999 | 1.00 | KDM4E (0.65) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL10018546 | 0.88 | KDM4E (0.62) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL14506244 | 0.85 | KDM4E (0.53) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL1884123 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL3360017 | 0.78 | DAO (1.00) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL15690621 | 0.76 | KDM4E (0.71) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL7807589 | 0.75 | DAO (0.80) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL2726546 | 0.74 | DAO (0.73) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL17942038 | 0.74 | KDM4E (0.69) | KDM4EALDH1A1MAPTIDEMPI | |
| SCHEMBL29505902 | 0.74 | DAO (0.73) | KDM4EALDH1A1MAPTIDEMPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6514951-B1 | LL-F28249 alpha-lambda or a 23-oxo or 23-imino derivative of | AMERICAN CYANAMID COMPANY | 2003-02-04 | — | — | US | disclosed |