Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 10/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6904308 | 0.81 | ATM (0.37) | ATMTACR1KDM4EALDH1A1HPGD | |
| SCHEMBL6918811 | 0.81 | ATM (0.34) | ATMTACR1KDM4EALDH1A1HPGD | |
| SCHEMBL6920657 | 0.76 | ALDH1A1 (0.41) | TACR1KDM4EALDH1A1HPGDCYP1A2 | |
| SCHEMBL6903632 | 0.75 | NOTUM (0.33) | — | |
| SCHEMBL6906142 | 0.74 | ATM (0.37) | ATMTACR1KDM4EALDH1A1HPGD | |
| SCHEMBL4202229 | 0.72 | ATM (0.51) | ATMTACR1KDM4EALDH1A1HPGD | |
| SCHEMBL6904728 | 0.72 | MEN1 (0.30) | — | |
| SCHEMBL310305 | 0.72 | TACR1 (0.44) | ATMTACR1KDM4EALDH1A1HPGD | |
| SCHEMBL6096533 | 0.68 | ATM (0.42) | ATMTACR1KDM4EALDH1A1HPGD | |
| SCHEMBL6903700 | 0.68 | KCNN4 (0.35) | TACR1ALDH1A1HPGDCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004111000-A2 | PIPERIDYL DERIVATIVES AND THEIR USE AS TACHYKININ ANTAGONISTS | ASTELLAS PHARMA INC. (JP) | 2004-12-23 | — | — | WO | disclosed |