Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2A | P48426 | 8/20 | 0.73 |
| ▸ | PIP4K2C | Q8TBX8 | 2/20 | 0.73 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | FADS1 | O60427 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RAF1 | P04049 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.52 |
| ▸ | KIT | P10721 | 1/20 | 0.52 |
| ▸ | FLT4 | P35916 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2376175 | 0.85 | MEN1 (0.72) | PIP4K2APIP4K2CPIP4K2BKMT2AMEN1 | |
| SCHEMBL6979258 | 0.79 | ABCG2 (0.69) | KMT2ARAB9ANPC1GAAEGFR | |
| SCHEMBL16363310 | 0.76 | KMT2A (0.73) | PIP4K2APIP4K2CPIP4K2BKMT2AMEN1 | |
| SCHEMBL30827872 | 0.76 | PIP4K2A (0.64) | PIP4K2APIP4K2CPIP4K2BKMT2AMEN1 | |
| SCHEMBL2987637 | 0.73 | EGFR (0.73) | KMT2AMEN1EGFR | |
| SCHEMBL3322206 | 0.72 | EGFR (0.56) | KMT2AMEN1EGFRRAF1 | |
| SCHEMBL13804575 | 0.72 | EGFR (0.56) | KMT2AMEN1EGFRRAF1 | |
| SCHEMBL3324098 | 0.72 | EGFR (0.57) | PIP4K2AKMT2AMEN1ALDH1A1EGFR | |
| SCHEMBL4258181 | 0.72 | ELANE (0.50) | PIP4K2APIP4K2CPIP4K2BRAB9ANPC1 | |
| SCHEMBL8807167 | 0.71 | EGFR (0.75) | EGFRKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004112714-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-12-29 | — | — | WO | disclosed |