Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | YAP1 | P46937 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867582 | 1.00 | KDM4E (0.47) | KDM4EPKMALDH1A1STSP2RX7 | |
| SCHEMBL7895983 | 1.00 | KDM4E (0.47) | KDM4EPKMALDH1A1STSP2RX7 | |
| SCHEMBL7341805 | 0.91 | KDM4E (0.48) | KDM4EPKMALDH1A1STSP2RX7 | |
| SCHEMBL7341808 | 0.91 | KDM4E (0.48) | KDM4EPKMALDH1A1STSP2RX7 | |
| SCHEMBL7490108 | 0.91 | KDM4E (0.48) | KDM4EPKMALDH1A1STSP2RX7 | |
| SCHEMBL22764722 | 0.88 | ALDH1A1 (0.44) | KDM4EPKMALDH1A1STSP2RX7 | |
| SCHEMBL22764858 | 0.88 | ALDH1A1 (0.44) | KDM4EPKMALDH1A1STSP2RX7 | |
| SCHEMBL22764857 | 0.88 | ALDH1A1 (0.44) | KDM4EPKMALDH1A1STSP2RX7 | |
| SCHEMBL31589019 | 0.88 | ALDH1A1 (0.44) | KDM4EPKMALDH1A1STSP2RX7 | |
| SCHEMBL29922297 | 0.88 | ALDH1A1 (0.44) | KDM4EPKMALDH1A1STSP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004058702-A2 | 4-[(4-(CARBOXYETHYL) PIPERIDINYL) METHYL] PYRROLIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2004-07-15 | — | — | WO | disclosed |