Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | HEXA | P06865 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6923371 | 1.00 | OGA (0.39) | OGASMN1; SMN2NPSR1CYP2C9CYP2C19 | |
| SCHEMBL6924333 | 1.00 | OGA (0.39) | OGASMN1; SMN2NPSR1CYP2C9CYP2C19 | |
| SCHEMBL6924328 | 1.00 | OGA (0.39) | OGASMN1; SMN2NPSR1CYP2C9CYP2C19 | |
| SCHEMBL6923365 | 1.00 | OGA (0.39) | OGASMN1; SMN2NPSR1CYP2C9CYP2C19 | |
| SCHEMBL6926533 | 0.81 | OGA (0.36) | OGASMN1; SMN2NPSR1 | |
| SCHEMBL6926539 | 0.81 | OGA (0.36) | OGASMN1; SMN2NPSR1 | |
| SCHEMBL6926536 | 0.81 | OGA (0.36) | OGASMN1; SMN2NPSR1 | |
| SCHEMBL6928345 | 0.80 | OGA (0.38) | OGASMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL6927102 | 0.80 | OGA (0.38) | OGASMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL6928335 | 0.80 | OGA (0.38) | OGASMN1; SMN2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518299-B1 | Trans-5-(1-Acetylamino-2-ethyl)butyl-1 -aminoiminomethylpyrrolidine-3-carboxylic acid | BIOCRYST PHARMACEUTICALS, INC. | 2003-02-11 | — | — | US | disclosed |