Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6928335 | 1.00 | OGA (0.38) | OGAHSD11B1MGAMGAASI | |
| SCHEMBL6927099 | 1.00 | OGA (0.38) | OGAHSD11B1MGAMGAASI | |
| SCHEMBL6927105 | 1.00 | OGA (0.38) | OGAHSD11B1MGAMGAASI | |
| SCHEMBL6928345 | 1.00 | OGA (0.38) | OGAHSD11B1MGAMGAASI | |
| SCHEMBL6924333 | 0.80 | OGA (0.39) | OGACYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL6924328 | 0.80 | OGA (0.39) | OGACYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL6923365 | 0.80 | OGA (0.39) | OGACYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL24663693 | 0.73 | HSD11B1 (0.43) | HSD11B1MGAMGAASIMGAM2 | |
| SCHEMBL31420603 | 0.72 | OGA (0.38) | OGACYP2C9CYP2C19 | |
| SCHEMBL27577146 | 0.72 | GBA1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518299-B1 | Trans-5-(1-Acetylamino-2-ethyl)butyl-1 -aminoiminomethylpyrrolidine-3-carboxylic acid | BIOCRYST PHARMACEUTICALS, INC. | 2003-02-11 | — | — | US | disclosed |