Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.49 |
| ▸ | MIF | P14174 | 6/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 8/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5924402 | 0.90 | KDM1A (0.45) | KDM1AMIFNOTUMBLMRXRA | |
| SCHEMBL5924375 | 0.90 | NOTUM (0.56) | KDM1AMIFNOTUMBLMRXRA | |
| SCHEMBL6926057 | 0.88 | MIF (0.48) | KDM1AMIFNOTUMRXRAGRIN1 | |
| SCHEMBL6923537 | 0.87 | KDM1A (0.47) | KDM1AMIFNOTUMBLMRXRA | |
| SCHEMBL5924396 | 0.87 | KDM1A (0.47) | KDM1AMIFNOTUMBLMRXRA | |
| SCHEMBL5924547 | 0.85 | KDM1A (0.46) | KDM1AMIFNOTUMRXRAGRIN1 | |
| SCHEMBL6923533 | 0.83 | KDM1A (0.41) | KDM1ANOTUMBLMRXRAGRIN1 | |
| SCHEMBL6505411 | 0.79 | MAOB (0.48) | KDM1AMIFNOTUMRXRAGRIN1 | |
| SCHEMBL6532325 | 0.77 | NOTUM (0.47) | KDM1AMIFNOTUMRXRAGRIN1 | |
| SCHEMBL5924471 | 0.77 | NOTUM (0.60) | KDM1AMIFNOTUMRXRAGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004101531-A1 | ANTIINFECTIVE 1,2,3-TRIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2004-11-25 | — | — | WO | disclosed |