SCHEMBL6923537

SCHEMBL6923537

OC(=S)NCc1cn(-c2ccc(-n3ccnc3)c(F)c2)nn1

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.47
MIF P14174 4/20 0.40
RXRA P19793 11/20 0.40
GRIN1 Q05586 11/20 0.40
GRIN2B Q13224 11/20 0.40
NOTUM Q6P988 1/20 0.40
KCNH2 Q12809 2/20 0.39
BLM P54132 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5924396 0.92 KDM1A (0.47) KDM1AMIFRXRAGRIN1GRIN2B
SCHEMBL5924547 0.90 KDM1A (0.46) KDM1AMIFRXRAGRIN1GRIN2B
SCHEMBL6926069 0.87 MIF (0.45) KDM1AMIFRXRAGRIN1GRIN2B
SCHEMBL5924375 0.87 NOTUM (0.56) KDM1AMIFRXRAGRIN1GRIN2B
SCHEMBL6923527 0.87 KDM1A (0.49) KDM1AMIFRXRAGRIN1GRIN2B
SCHEMBL5924402 0.85 KDM1A (0.45) KDM1AMIFRXRAGRIN1GRIN2B
SCHEMBL6923533 0.80 KDM1A (0.41) KDM1ARXRAGRIN1GRIN2BNOTUM
SCHEMBL6505423 0.78 MAOB (0.47) KDM1AMIFRXRAGRIN1GRIN2B
SCHEMBL5924503 0.78 MIF (0.43) KDM1AMIFRXRAGRIN1GRIN2B
SCHEMBL5924267 0.76 KDM1A (0.44) KDM1AMIFRXRAGRIN1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004101531-A1 ANTIINFECTIVE 1,2,3-TRIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM DR. REDDY'S LABORATORIES LTD. (IN) 2004-11-25 WO disclosed