Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 10/20 | 0.56 |
| ▸ | GRIN3B | O60391 | 10/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 10/20 | 0.56 |
| ▸ | GRIN2A | Q12879 | 10/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.56 |
| ▸ | GRIN2C | Q14957 | 10/20 | 0.56 |
| ▸ | GRIN3A | Q8TCU5 | 10/20 | 0.56 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3260447 | 0.72 | GRIN2D (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8895602 | 0.71 | GRIN2D (0.76) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9410631 | 0.71 | EGLN1 (0.48) | GAALMNAMAPTHPGDKMT2A | |
| SCHEMBL7308279 | 0.70 | PARP1 (0.47) | PDPK1DAOHPGD | |
| SCHEMBL8872873 | 0.70 | GRIN2D (0.82) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8895896 | 0.69 | GRIN2D (0.66) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8897535 | 0.69 | GRIN2D (0.72) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9410629 | 0.68 | FEN1 (0.47) | GAALMNAMAPTHPGDKMT2A | |
| SCHEMBL9410625 | 0.68 | FEN1 (0.38) | POLBL3MBTL1LMNACYP1A2CYP3A4 | |
| SCHEMBL8898836 | 0.68 | GRIN2D (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |