Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.46 |
| ▸ | RPA1 | P27694 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829658 | 0.81 | HTT (0.45) | TERTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6831211 | 0.80 | TERT (0.48) | TERTRPA1ALDH1A1MEN1KMT2A | |
| SCHEMBL11407999 | 0.78 | RPA1 (0.44) | RPA1ALDH1A1HPGDTPMTMEN1 | |
| SCHEMBL11904537 | 0.72 | TDP1 (0.61) | ALDH1A1HPGDMEN1KMT2ANPSR1 | |
| SCHEMBL38726 | 0.72 | TDP1 (0.61) | ALDH1A1HPGDMEN1KMT2ANPSR1 | |
| SCHEMBL3065831 | 0.71 | RPA1 (0.64) | RPA1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL23727166 | 0.70 | TDP1 (0.58) | ALDH1A1HPGDMEN1KMT2ANPSR1 | |
| Bromide SCHEMBL20513084 | 0.70 | TDP1 (0.58) | ALDH1A1HPGDMEN1KMT2ANPSR1 | |
| Ammonia Solution, Strong SCHEMBL16240294 | 0.70 | TDP1 (0.58) | ALDH1A1HPGDMEN1KMT2ANPSR1 | |
| Fluoride SCHEMBL20513066 | 0.70 | TDP1 (0.58) | ALDH1A1HPGDMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |