SCHEMBL692374

SCHEMBL692374

C=C(C)C(=O)OCCC[Si](C)(C)Cl

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.55
THRB P10828 1/20 0.47
POLB P06746 1/20 0.42
APEX1 P27695 1/20 0.42
HTT P42858 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8962565 0.95 TSHR (0.58) TSHRTHRBPOLBAPEX1HTT
Hexane SCHEMBL28941486 0.93 TSHR (0.67) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23322166 0.93 TSHR (0.61) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23321704 0.93 TSHR (0.61) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23321719 0.93 TSHR (0.61) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23321653 0.93 TSHR (0.61) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23322075 0.93 TSHR (0.61) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23321741 0.93 TSHR (0.61) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23321624 0.93 TSHR (0.61) TSHRTHRBPOLBAPEX1HTT
SCHEMBL23322177 0.93 TSHR (0.61) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1646 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037662-A Water-based gloss oil with flame color anti-counterfeiting function, and preparation method and detection method thereof 上海高邦印刷材料有限公司 2026-05-15 CN claimed
EP-4535997-A1 ANTIMICROBIAL AND/OR ANTIVIRAL MATERIALS Klura Ltd (GB) 2025-04-16 EP claimed
CN-119642084-A Fireproof high-pressure hydrogen storage cylinder and preparation method thereof 沈阳欧施盾新材料科技有限公司 2025-03-18 CN claimed
US-20240409563-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME GELEST, INC. 2024-12-12 US claimed
EP-4448536-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME GELEST, INC. (US) 2024-10-23 EP claimed
CN-118401532-A High-purity polysiloxane macromer and preparation method thereof 盖列斯特有限公司 2024-07-26 CN claimed
CN-118221944-A Preparation method of acrylic ester modified silicone oil for silicone hydrogel type contact lens 苏州矽合高新材料科技有限公司 2024-06-21 CN claimed
CN-118108947-A Preparation of methacrylate double-end-capped dimethyl silicone oil for contact lens 苏州矽合高新材料科技有限公司 2024-05-31 CN claimed
EP-4363498-A1 HIGH WATER CONTENT BIOMEDICAL DEVICES Bausch + Lomb Ireland Limited (IE) 2024-05-08 EP claimed
WO-2024074830-A1 ANTIMICROBIAL AND/OR ANTIVIRAL MATERIALS CODIKOAT LTD (GB) 2024-04-11 WO claimed
WO-1996039458-A1 CURABLE SILICONE SEALANT/ADHESIVE COMPOSITIONS LOCTITE CORPORATION (US) 1996-12-12 WO claimed
US-5567789-A Method for the preparation of organopolysiloxanes DOW CORNING TORAY SILICONE CO., LTD. (JP) 1996-10-22 US claimed
US-5567790-A Method for the preparation of diphenylsiloxane-dimethylsiloxane copolymers DOW CORNING TORAY SILICONE CO., LTD. (JP) 1996-10-22 US claimed
US-5493039-A Method for the preparation of methacryloxypropyldimethylchlorosilane DOW CORNING TORAY SILICONE CO., LTD. (JP) 1996-02-20 US claimed
EP-0693492-A1 Method for preparation of methacryloxypropyldimethylchlorosilane Dow Corning Toray Silicone Company, Limited (JP) 1996-01-24 EP claimed
EP-0693521-A1 Method for the preparation of diphenylsiloxane-dimethylsiloxane copolymers Dow Corning Toray Silicone Company, Limited (JP) 1996-01-24 EP claimed
EP-0693520-A1 Method for the preparation of organopolysiloxanes Dow Corning Toray Silicone Company, Limited (JP) 1996-01-24 EP claimed
US-5190828-A Low-gloss polyacetal resin compositions and molded articles POLYPLASTICS CO., LTD. (JP) 1993-03-02 US claimed
US-5023159-A Encapsulated electrophotographic toner compositions XEROX CORPORATION (US) 1991-06-11 US claimed
EP-0268243-A2 Packing material and process for its production Tosoh Corporation (JP) 1988-05-25 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240409563-A1 HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME SSRP1, RPLP2, RPLP1 TSHR 1897/4885THRB 2939/4885POLB 307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.