SCHEMBL6923760

SCHEMBL6923760

NNC(=O)C[C@H](N)C(=O)NN

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.42
KDM4E B2RXH2 2/20 0.37
CTSD P07339 2/20 0.37
KDM5C P41229 1/20 0.37
PHF8 Q9UPP1 1/20 0.37
KDM2A Q9Y2K7 1/20 0.37
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
PDF Q9HBH1 1/20 0.31
SLC1A3 P43003 1/20 0.31
SLC1A2 P43004 1/20 0.31
SLC1A1 P43005 1/20 0.31
CYP1A2 P05177 1/20 0.30
TSHR P16473 1/20 0.30
NFKB1 P19838 1/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
THPO P40225 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2113218 1.00 HIF1A (0.42) HIF1AKDM4ECTSDKDM5CPHF8
SCHEMBL15713100 0.84 HIF1A (0.37) HIF1ACTSDALDH1A1LMNACA1
SCHEMBL28509229 0.80 HIF1A (0.42) HIF1ACTSDLMNACA1CA2
SCHEMBL1372611 0.80 HIF1A (0.42) HIF1AKDM4ECTSDKDM5CPHF8
SCHEMBL12906559 0.80 GRIK1 (0.48) KDM4EKDM5CPHF8KDM2ASLC1A3
SCHEMBL24667461 0.80 GRIK1 (0.48) KDM4EKDM5CPHF8KDM2ASLC1A3
SCHEMBL9921298 0.80 HIF1A (0.42) HIF1ACTSDLMNACA1CA2
SCHEMBL5819782 0.80 HIF1A (0.42) HIF1AKDM4ECTSDKDM5CPHF8
SCHEMBL15131243 0.80 KDM4E (0.37) HIF1AKDM4ECTSDKDM5CPHF8
SCHEMBL27468494 0.80 HIF1A (0.42) HIF1AKDM4ECTSDKDM5CPHF8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1012208-A4 CROSS-LINKED PARTICLES ACCESS PHARMACEUTICALS AUSTRAL (AU) 2003-06-18 EP claimed
US-6221397-B1 POLYMER CONTAINING REACTIVE GROUPS SELECTED FROM THE GROUP CONSISTING OF CARBOXYL, HYDRAZIDYL, AMINO AND THIOL GROUPS, COVALENTLY LINKED TO A DIHYDRAZIDE SPACER BIOTECH AUSTRALIA PTY LIMITED (AU) 2001-04-24 US claimed
EP-1012208-A1 CROSS-LINKED PARTICLES BIOTECH AUSTRALIA PTY. LIMITED (AU) 2000-06-28 EP claimed
WO-1999011703-A1 CROSS-LINKED PARTICLES BIOTECH AUSTRALIA PTY. LIMITED (US) 1999-03-11 WO claimed
US-9169339-B2 Curable composition, molded product and method for producing molded product DAIKIN INDUSTRIES, LTD. (JP) 2015-10-27 US disclosed
US-20130190456-A1 CURABLE COMPOSITION, MOLDED ARTICLE AND METHOD FOR PRODUCING MOLDED ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2013-07-25 US disclosed
WO-2012077583-A1 CURABLE COMPOSITION, MOLDED PRODUCT AND METHOD FOR PRODUCING MOLDED PRODUCT DAIKIN INDUSTRIES, LTD. (JP) 2012-06-14 WO disclosed
EP-1012208-A4 CROSS-LINKED PARTICLES ACCESS PHARMACEUTICALS AUSTRAL (AU) 2003-06-18 EP disclosed
US-6221397-B1 POLYMER CONTAINING REACTIVE GROUPS SELECTED FROM THE GROUP CONSISTING OF CARBOXYL, HYDRAZIDYL, AMINO AND THIOL GROUPS, COVALENTLY LINKED TO A DIHYDRAZIDE SPACER BIOTECH AUSTRALIA PTY LIMITED (AU) 2001-04-24 US disclosed
EP-1012208-A1 CROSS-LINKED PARTICLES BIOTECH AUSTRALIA PTY. LIMITED (AU) 2000-06-28 EP disclosed
WO-1999011703-A1 CROSS-LINKED PARTICLES BIOTECH AUSTRALIA PTY. LIMITED (US) 1999-03-11 WO disclosed