SCHEMBL24667461

SCHEMBL24667461

NNC(=O)C[C@H](N)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 6/20 0.48
GRIK2 Q13002 3/20 0.48
GRM1 Q13255 2/20 0.48
GRM2 Q14416 2/20 0.48
SLC7A5 Q01650 1/20 0.46
SLC1A1 P43005 6/20 0.46
SLC1A3 P43003 5/20 0.46
SLC1A2 P43004 5/20 0.46
PTGS1 P23219 1/20 0.44
SLC7A11 Q9UPY5 1/20 0.44
GGT1 P19440 4/20 0.43
KDM4E B2RXH2 1/20 0.42
KDM5C P41229 1/20 0.42
PHF8 Q9UPP1 1/20 0.42
KDM2A Q9Y2K7 1/20 0.42
GRIA4 P48058 3/20 0.42
GRIK3 Q13003 3/20 0.42
GRIK5 Q16478 3/20 0.42
GRIA2 P42262 2/20 0.41
GRM8 O00222 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12906559 1.00 GRIK1 (0.48) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL9684668 0.80 FOLH1 (0.48) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL6923760 0.80 HIF1A (0.42) SLC1A1SLC1A3SLC1A2KDM4EKDM5C
SCHEMBL10596071 0.80 FOLH1 (0.48) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL2113218 0.80 HIF1A (0.42) SLC1A1SLC1A3SLC1A2KDM4EKDM5C
SCHEMBL15131243 0.80 KDM4E (0.37) SLC1A1SLC1A3SLC1A2KDM4EKDM5C
SCHEMBL3875073 0.78 GRIK1 (0.46) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL8368782 0.78 SLC7A5 (0.50) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL359673 0.78 SLC7A5 (0.50) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL515168 0.78 SLC7A5 (0.50) GRIK1GRIK2GRM1GRM2SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240167070-A1 METHODS FOR CYCLIZATION OF (POLY)PEPTIDES COMPRISING Ny-HYDROXY- OR Ny-AMINO-L-ASPARAGINE NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2024-05-23 US claimed
CN-1829683-A Mildronate, preparation method thereof and pharmaceutical composition based on mildronate GRINDEKS JSC (LV) 2006-09-06 CN claimed
EP-4558176-A1 HYDROGELS AND METHODS OF USING THE SAME Rowan University (US) 2025-05-28 EP disclosed
US-20240167070-A1 METHODS FOR CYCLIZATION OF (POLY)PEPTIDES COMPRISING Ny-HYDROXY- OR Ny-AMINO-L-ASPARAGINE NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2024-05-23 US disclosed
WO-2024020558-A1 HYDROGELS AND METHODS OF USING THE SAME ROWAN UNIVERSITY (US) 2024-01-25 WO disclosed
WO-2022186782-A1 METHODS FOR CYCLIZATION OF (POLY)PEPTIDES COMPRISING Nγ-HYDROXY- OR Nγ-AMINO-L-ASPARAGINE NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2022-09-09 WO disclosed
WO-2022186782-A1 METHODS FOR CYCLIZATION OF (POLY)PEPTIDES COMPRISING Nγ-HYDROXY- OR Nγ-AMINO-L-ASPARAGINE NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2022-09-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240167070-A1 METHODS FOR CYCLIZATION OF (POLY)PEPTIDES COMPRISING Ny-HYDROXY- OR Ny-AMINO-L-ASPARAGINE ANPEP, DNPEP, ASNS GRIK1 2797/4885GRIK2 3215/4885GRM1 4107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.