Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13239923 | 0.87 | TP53 (0.57) | KDM4ETP53LMNAALDH1A1CYP3A4 | |
| SCHEMBL29888943 | 0.86 | NFE2L2 (0.42) | KDM4ETP53LMNAALDH1A1CYP3A4 | |
| SCHEMBL4302733 | 0.86 | NFE2L2 (0.42) | KDM4ETP53LMNAALDH1A1CYP3A4 | |
| SCHEMBL2424023 | 0.86 | CA1 (0.41) | KDM4ETP53LMNAALDH1A1CYP3A4 | |
| SCHEMBL20627685 | 0.83 | CA1 (0.50) | KDM4ETP53LMNAALDH1A1CYP3A4 | |
| SCHEMBL7122164 | 0.83 | CA1 (0.50) | KDM4ETP53LMNAALDH1A1CYP3A4 | |
| SCHEMBL21668256 | 0.82 | POLB (0.44) | KDM4ETP53LMNAALDH1A1CYP3A4 | |
| SCHEMBL13712993 | 0.81 | KDM4E (0.47) | KDM4ETP53LMNAALDH1A1CYP3A4 | |
| Methyl Alcohol SCHEMBL27577395 | 0.81 | KDM4E (0.54) | KDM4ETP53LMNAALDH1A1CYP3A4 | |
| SCHEMBL9814047 | 0.80 | KDM4E (0.53) | KDM4ETP53LMNAALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073612-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO. INC. (US) | 2004-09-02 | — | — | WO | disclosed |
| EP-0149976-A2 | Substituted imidazoles | CIBA-GEIGY AG (CH) | 1985-07-31 | — | — | EP | disclosed |