Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | GRM8 | O00222 | 1/20 | 0.48 |
| ▸ | GRM6 | O15303 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.48 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.48 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.48 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14788859 | 0.82 | SLC1A2 (0.48) | GSRCYP1A2GRM8GRM6GRIN2D | |
| SCHEMBL28267787 | 0.81 | GRM8 (0.67) | GSRCYP1A2GRM8GRM6GRIN2D | |
| SCHEMBL29067249 | 0.79 | GSR (0.45) | GSRCYP1A2GRM8GRM6GRIN2D | |
| SCHEMBL29067251 | 0.79 | GSR (0.45) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Glutarate SCHEMBL8508814 | 0.79 | GSR (0.64) | GSRCYP1A2GRM8GRM6GRIN2D | |
| (S)-2-Aminoadipic Acid SCHEMBL8508273 | 0.78 | GSR (0.59) | GSRCYP1A2GRM8GRM6GRIN2D | |
| (S)-2-Aminoadipic Acid SCHEMBL20913706 | 0.77 | GSR (0.69) | GSRCYP1A2GRM8GRM6GRIN2D | |
| (S)-2-Aminoadipic Acid SCHEMBL41328 | 0.76 | GSR (0.73) | GSRCYP1A2GRM8GRM6GRIN2D | |
| (S)-2-Aminoadipic Acid SCHEMBL97323 | 0.76 | GSR (0.73) | GSRCYP1A2GRM8GRM6GRIN2D | |
| (S)-2-Aminoadipic Acid SCHEMBL2022365 | 0.76 | GSR (0.73) | GSRCYP1A2GRM8GRM6GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6582700-B1 | A linear core chain having two or more side chains pending directly from different points on the linear core chain. Each of the side chains comprises an epitopic site of an antigen or a peptide. The synthetic constructs are monomeric units that | MEDICAL UNIVERSITY OF SOUTH CAROLINA | 2003-06-24 | — | — | US | disclosed |
| EP-1032422-A4 | LINEAR ANTIGEN SUPPORTING UNITS | UNIV SOUTH CAROLINA (US) | 2003-02-05 | — | — | EP | disclosed |
| EP-1032422-A1 | LINEAR ANTIGEN SUPPORTING UNITS | MEDICAL UNIVERSITY OF SOUTH CAROLINA (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999025381-A1 | LINEAR ANTIGEN SUPPORTING UNITS | MEDICAL UNIVERSITY OF SOUTH CAROLINA (US) | 1999-05-27 | — | — | WO | disclosed |