SCHEMBL6924313

SCHEMBL6924313

CCC(C(=O)O)(c1ccc(C(=O)OC(C)(C)C)cc1)c1ccccc1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C19 P33261 1/20 0.44
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
ABCG2 Q9UNQ0 1/20 0.37
TDP1 Q9NUW8 3/20 0.36
ALDH1A1 P00352 2/20 0.36
TSHR P16473 2/20 0.36
HSD17B10 Q99714 1/20 0.36
MAPT P10636 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TNF P01375 1/20 0.35
KLF5 Q13887 1/20 0.35
NOD1 Q9Y239 1/20 0.35
SLC7A5 Q01650 1/20 0.35
CHRM2 P08172 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5163394 0.78 ALDH1A1 (0.47) CA12CA1CA2CA9CA14
SCHEMBL6924512 0.74 CYP2C9 (0.51) CYP1A2CYP2D6CYP2C19CA12CA1
SCHEMBL6924319 0.73 CYP2C9 (0.42) CYP1A2CYP2D6CYP2C19CA12CA1
SCHEMBL14666430 0.72 CA1 (0.47) CYP1A2CYP2D6CYP2C19CA12CA1
Hydrogen Peroxide SCHEMBL28425777 0.71 TDP1 (0.64) CYP1A2CYP2D6CYP2C19CA12CA1
SCHEMBL29199324 0.71 TDP1 (0.64) CYP1A2CYP2D6CYP2C19CA12CA1
SCHEMBL260960 0.71 TDP1 (0.64) CYP1A2CYP2D6CYP2C19CA12CA1
Hydrogen Peroxide SCHEMBL28474133 0.71 TDP1 (0.64) CYP1A2CYP2D6CYP2C19CA12CA1
Hydrochloric Acid SCHEMBL23276979 0.69 TDP1 (0.62) CYP1A2CYP2D6CYP2C19CA12CA1
SCHEMBL19895794 0.69 TDP1 (0.62) CYP1A2CYP2D6CYP2C19CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6515011-B2 Anticoagulants MERCK & CO., INC. 2003-02-04 US disclosed