Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 8/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TOP1 | P11387 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4960324 | 0.96 | NQO1 (0.57) | NQO1MEN1KMT2ACYP2C9CRHBP | |
| SCHEMBL4958904 | 0.92 | MEN1 (0.57) | NQO1MEN1KMT2ACYP2C9CRHBP | |
| SCHEMBL4959579 | 0.85 | ADORA3 (0.60) | NQO1MEN1KMT2ACYP2C9CRHBP | |
| SCHEMBL5107208 | 0.84 | ADORA3 (0.53) | NQO1MEN1KMT2ACYP2C9CRHBP | |
| SCHEMBL4960715 | 0.82 | ADORA3 (0.51) | NQO1MEN1KMT2ACYP2C9CRHBP | |
| SCHEMBL4960881 | 0.80 | NQO1 (0.60) | NQO1MEN1KMT2ACYP2C9CRHBP | |
| SCHEMBL7219960 | 0.79 | NQO1 (0.44) | NQO1MEN1KMT2ACYP2C9ADORA3 | |
| SCHEMBL4962535 | 0.78 | NQO1 (0.58) | NQO1CYP2C9CRHBPCASP7CASP6 | |
| SCHEMBL8868322 | 0.77 | VKORC1 (0.69) | NQO1MEN1KMT2ACYP2C9NFKB1 | |
| SCHEMBL1649145 | 0.75 | ADORA3 (0.65) | NQO1MEN1KMT2ACYP2C9CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383756-A1 | COUMARIN DERIVATIVES TO BE USED AS ANTICOAGULANTS | Arxy Therapeutics (US) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002085882-A1 | COUMARIN DERIVATIVES TO BE USED AS ANTICOAGULANTS | ARXY THERAPEUTICS (US) | 2002-10-31 | — | — | WO | disclosed |