Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 15/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270377 | 0.83 | LRRK2 (0.38) | TLR8TLR7 | |
| SCHEMBL7093237 | 0.81 | TLR8 (0.34) | TLR8TLR7PRMT5 | |
| SCHEMBL7093493 | 0.81 | MAPT (0.39) | — | |
| SCHEMBL8133953 | 0.75 | TLR8 (0.41) | TLR8TLR7PRMT5 | |
| SCHEMBL5513106 | 0.72 | TLR8 (0.41) | TLR8TLR7PRMT5 | |
| SCHEMBL3355697 | 0.71 | TLR8 (0.36) | TLR8TLR7PRMT5 | |
| SCHEMBL301016 | 0.70 | TLR8 (0.38) | TLR8TLR7PRMT5 | |
| SCHEMBL29508372 | 0.70 | TLR8 (0.40) | TLR8TLR7 | |
| SCHEMBL13914459 | 0.68 | KDM4E (0.36) | TLR8TLR7PRMT5 | |
| SCHEMBL4403098 | 0.65 | SYK (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6514985-B1 | Induce the biosynthesis of cytokines such as interferon and tumor necrosis factor; exhibit antiviral and antitumor properties | 3M INNOVATIVE PROPERTIES COMPANY | 2003-02-04 | — | — | US | disclosed |
| EP-1040112-A1 | IMIDAZONAPHTHYRIDINES AND THEIR USE IN INDUCING CYTOKINE BIOSYNTHESIS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999029693-A1 | IMIDAZONAPHTHYRIDINES AND THEIR USE IN INDUCING CYTOKINE BIOSYNTHESIS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-06-17 | — | — | WO | disclosed |