Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 8/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29508394 | 0.91 | TLR8 (0.41) | TLR8TLR7KCNH2LRRK2SLC2A1 | |
| SCHEMBL28674921 | 0.91 | TLR8 (0.41) | TLR8TLR7KCNH2LRRK2SLC2A1 | |
| SCHEMBL5270377 | 0.86 | LRRK2 (0.38) | TLR8TLR7KCNH2LRRK2SLC2A1 | |
| SCHEMBL29508383 | 0.84 | TLR8 (0.40) | TLR8TLR7KCNH2LRRK2SLC2A1 | |
| SCHEMBL29508384 | 0.83 | KCNH2 (0.38) | TLR8TLR7KCNH2LRRK2SLC2A1 | |
| SCHEMBL28681620 | 0.83 | KCNH2 (0.38) | TLR8TLR7KCNH2LRRK2SLC2A1 | |
| SCHEMBL1034069 | 0.82 | MEN1 (0.36) | LRRK2LMNASMN1; SMN2NPSR1PDE4B | |
| SCHEMBL23924991 | 0.82 | LRRK2 (0.36) | TLR8TLR7LRRK2SLC2A1SMN1; SMN2 | |
| SCHEMBL23924989 | 0.82 | LRRK2 (0.36) | TLR8TLR7LRRK2SLC2A1SMN1; SMN2 | |
| SCHEMBL23924927 | 0.81 | LRRK2 (0.38) | LRRK2SMN1; SMN2PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3980415-A1 | N-1 BRANCHED ALKYL SUBSTITUTED IMIDAZO[4,5-C]QUINOLINE COMPOUNDS, COMPOSITIONS, AND METHODS | 3M Innovative Properties Company (US) | 2022-04-13 | — | — | EP | disclosed |