Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.39 |
| ▸ | PGK2 | P07205 | 1/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.37 |
| ▸ | PGD | P52209 | 3/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SELP | P16109 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.35 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.35 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24705822 | 0.83 | LPAR5 (0.46) | PGK1PGK2LPAR5PGDMPI | |
| SCHEMBL12281492 | 0.83 | LPAR5 (0.46) | PGK1PGK2LPAR5PGDMPI | |
| SCHEMBL12283377 | 0.83 | LPAR5 (0.46) | PGK1PGK2LPAR5PGDMPI | |
| SCHEMBL12284731 | 0.83 | LPAR5 (0.46) | PGK1PGK2LPAR5PGDMPI | |
| SCHEMBL12282822 | 0.83 | LPAR5 (0.46) | PGK1PGK2LPAR5PGDMPI | |
| SCHEMBL213379 | 0.83 | PGK1 (0.52) | PGK1PGK2LPAR5PGDMPI | |
| SCHEMBL7340 | 0.83 | PGK1 (0.52) | PGK1PGK2LPAR5PGDMPI | |
| SCHEMBL14278847 | 0.83 | PGK1 (0.52) | PGK1PGK2LPAR5PGDMPI | |
| SCHEMBL14278848 | 0.83 | PGK1 (0.52) | PGK1PGK2LPAR5PGDMPI | |
| SCHEMBL7341 | 0.83 | PGK1 (0.52) | PGK1PGK2LPAR5PGDMPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242440-A4 | USE OF NICOTINAMIDE ADENINE DINUCLEOTIDE (NAD) AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (NADP) ANALOGS TO MEASURE ENZYME ACTIVITIES, METABOLITES AND SUBSTRATES | SPECIALTY ASSAYS INC (US) | 2003-01-15 | — | — | EP | disclosed |
| EP-1242440-A2 | USE OF NICOTINAMIDE ADENINE DINUCLEOTIDE (NAD) AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (NADP) ANALOGS TO MEASURE ENZYME ACTIVITIES, METABOLITES AND SUBSTRATES | Specialty Assays, Inc. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001049247-A2 | ASSAYS FOR ANALYTES AND ENZYMES PRACTICED IN THE PRESENCE OF NAD AND NADP ANALOGUES, AND RELATED ASSAY KITS | SPECIALTY ASSAYS, INC. (US) | 2001-07-12 | — | — | WO | disclosed |