SCHEMBL6925097

SCHEMBL6925097

O=C1O[C@H](CO)CN1c1ccc(C2=CCN(Cc3ccccc3)CC2)c(F)c1

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CALML3 P27482 6/20 0.58
MAOA P21397 11/20 0.47
CYP2C19 P33261 2/20 0.46
CYP2C9 P11712 1/20 0.46
MAOB P27338 3/20 0.46
CYP3A4 P08684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5236580 1.00 CALML3 (0.58) CALML3MAOACYP2C19CYP2C9MAOB
SCHEMBL5625330 1.00 CALML3 (0.58) CALML3MAOACYP2C19CYP2C9MAOB
Trifluoroacetic Acid SCHEMBL5623895 0.95 CALML3 (0.54) CALML3MAOACYP2C19CYP2C9MAOB
SCHEMBL4016280 0.91 CALML3 (0.47) CALML3MAOA
SCHEMBL7256130 0.91 CALML3 (0.47) CALML3MAOA
SCHEMBL5233293 0.89 CALML3 (0.48) CALML3MAOACYP2C19CYP2C9MAOB
SCHEMBL5833839 0.89 CALML3 (0.48) CALML3MAOACYP2C19CYP2C9MAOB
SCHEMBL7256142 0.88 CALML3 (0.45) CALML3MAOACYP3A4
SCHEMBL6827066 0.88 MAOA (0.64) CALML3MAOAMAOB
SCHEMBL6827071 0.88 MAOA (0.64) CALML3MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004113329-A1 OXAZOLE DERIVATIVES AS ANTIBACTERIAL AGENTS ORCHID CHEMICALS AND PHARMACEUTICALS LTD. (IN) 2004-12-29 WO disclosed
WO-2003097640-A1 OXAZOLIDINONE DERIVATIVES AS ANTIBACTERIAL AGENTS ORCHID CHEMICALS & PHARMACEUTICALS LTD. (IN) 2003-11-27 WO disclosed